Protein-ProteinInteractions相关论文
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Peptides play a crucial in controlling and modulating protein-protein interactions and gain a wide research interest.How......
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Comparative protein-protein interaction analysis predicates distinct signature networks of metastati
Gene signatures of metastasis could be population specific.Precision cancer therapy focuses on ethnic groups and individ......
Targeting trimeric transmembrane domain 5 of oncogenic latent membrane protein 1 using a computation
Protein-protein interactions are involved in nearly all biological processes.These interactions are therefore vital drug......
Pyrimidine Triazole Thioether Derivatives as Toll-Like Receptor 5(TLR5)/Flagellin Complex Inhibitors
Protein-protein interactions have been regarded as "undruggable"despite their imporatance in many biological processes......
The protein-protein and protein-nucleic acid interfaces have been regarded as“undruggable” despite their importance in......
Screening of Small-Molecule Inhibitors of Protein-Protein Interaction with Capillary Electrophoresis
A simple and effective method for identifying inhibitors of protein-protein interactions(PPIs)was developed by using cap......
The disruption of protein-protein interactions with co-chaperones and client substrates as a strateg
The 90-kiloDalton (kD) heat shock protein (Hsp90) is a ubiquitous,ATP-dependent molec-ular chaperone whose primary funct......
Optogenetic Control of Phosphatidylinositol (3,4,5)-Triphosphate Production by Light-Sensitive Crypt
Main observation and conclusionrnPhosphatidylinositol (3,4,5)-triphosphate (PIP3),acting as a fundamental second messeng......
Genetically Encoded Residue Selective Photo-Crosslinker to Capture and Identify Protein Interactions
The genetically encoded non-selective photo-crosslinkers suffer from unpredictable crosslinking sites and false posi......
Protein kinases and their substrates comprise extensive signaling networks that regulate many diverse cellular funct......
Comparative Study of Elastic Network Model and Protein Contact Network for Protein Complexes the Hem
The overall topology and interracial interactions play key roles in understanding structural and functional principl......
A hybrid docking strategy to incorporate interface information for blind predictions of protein-prot
New demands and expectations for predicting protein-protein interactions have been emerging with the development of ......
Developing Cross-linking Mass Spectrometry(XL-MS)Strategies to Define Interaction and Structural Dyn
Protein-protein interactions(PPIs)are fundamental to protein structure and function.Perturbations of PPIs can cause ......
Toxoplasma gondii microneme proteins(TgMICs)are secreted by micronemes upon contact with host cells,and involved in ......
Assisted-Hopping Mechanism for Protein-DNA Binding in Sox2-Oct1-Hoxb1 Ternary Complex Evidenced from
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The overwhelming majority of antibiotics in clinical use are natural products isolated from Actinobacteria or semi-s......
Over the last decade, a new technique termed "Genetic-code Expansion" has become a highly powerful method for introd......
